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Adjanie Patabendige

Dr Patabendige is a Senior Lecturer in Biomedical Science and leads the Brain Barriers Research group ( at Edge Hill University. Her main goal is to improve fundamental knowledge in the mechanisms of disrupted brain barriers and fluids in neurological diseases.  


Current research interests


Development and establishment of physiologically-relevant in vitro models

Using a range of in vitro blood-brain barrier (BBB) models, we aim to understand the detailed cellular and molecular mechanisms of BBB dysfunction in neurological and cardiovascular diseases, including identification of new disease biomarkers. 


Understanding the pathophysiology of ischaemic stroke

Investigating the mechanisms involved in the pathophysiology of impaired brain fluid homeostasis in ischaemic stroke, including clinical translation and potential treatment strategies to reduce intracranial pressure elevation.   

BBB disruption