News and Impact
New NHS ENGLAND PhD INTERNSHIP OPPORTUNITY
This NHS England PhD internship will involve joint working with Lancashire Teaching Hospitals NHS Foundation Trust to evaluate the implementation of automated clinical coding on neurology clinic letters. Our previous work in this area looked at the evaluation of pre-trained named entity recognition and linking (NER+L) models. This effectively groups identified concepts together and assigns SNOMED-CT classification. The Medical Concept Annotation Toolkit (MedCAT) was used within the LANDER (Lancashire Data Science Environment) Trusted Research Environment (TRE) in Azure to identify and link concepts.
Co-creation of digital health technologies for management of functional neurological disorders (FND)
This is a workshop to be hosted by the University of Central Lancashire (UCLan) on 11/10/23.
For registration, please use this link. Co-creation of digital health technologies for FND management Tickets, Wed 11 Oct 2023 at 09:00 | Eventbrite.
This will be attended by most of the active researchers in FND in UK, including Prof Jon Stone, Prof Alan Carson, Prof Richard Brown and Dr Mahinda Yogarajah, among others.
LANCASHIRE NEUROSCIENCE MEDICAL STUDENT BECOMES National Neurology officer for NANSIG - the neurology and neurosurgery interest group
Siddarth Kannan has been appointed as national neurology officer for NANSIG - the Neurology and Neurosurgery Interest Group
first large-scale analysis of neurological emergency admissions in England
In this BMJ Open paper, Lancashire Neuroscience researchers in collaboration with the Office for Health Improvement and Disparities, report the number and types of emergency admissions using the Hospital Episode Statistics dataset.
NHSX PhD internship collaboration
This NHSX PhD internship opportunity with Lancashire Teaching Hospitals NHS Foundation Trust and Lancaster University will seek to enrich neurology patient information using MedCAT.
LANCASHIRE NEUROSCIENCE RESEARCH SHOWCASED AT RECENT LANCASTER UNIVERSITY EVENT
At a recent Lancaster Medical School research strategy event held jointly with regional NHS organisations and other partners, there was opportunity for research by Lancashire Neuroscience to be showcased.
RESEARCH GRANT SUCCESS FOR LANCASTER UNIVERSITY ACADEMIC CLINICAL LECTURER
Dr Al-Bachari has recently secured two separate research grants, one from the Dowager Countess Eleanor Peel Trust, the other from the Academy of Medical Sciences, to support the ENIGMA-PD-Vasc work.
LANCASHIRE TEACHING HOspitals contributes to work on covid-19 vaccine associated cerebral venous thrombosis cases
LANCASTER UNIVERSITY-PUBLIC HEALTH ENGLAND COLLABORATION
A new collaboration between Lancaster University and Public Health England will work on routine data pertaining to neurological emergency admissions in England. Professors Emsley and Knight are currently working on the first large scale analysis of neurological emergency admissions in England.
SANAD-II RESULTS PUBLISHED
SANAD-II was the study of standard and new antiepileptics drugs II. Lancashire Teaching Hospitals NHS Foundation Trust contributed participants to the trial. There were two arms to the trial, one in focal epilepsy and the other in generalised and unclassifiable epilepsy.
The SANAD-II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy published its results in the Lancet. Its findings did not support the use of levetiracetam or zonisamide as first-line treatments for patients with focal epilepsy. Lamotrigine should remain a first-line treatment for patients with focal epilepsy and should be the standard treatment in future trials.
The SANAD-II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy has published its results in the Lancet. The study found that compared with valproate, levetiracetam was found to be neither clinically effective nor cost-effective.
GLP-1 RECEPTOR AGONISTS AS POTENTIAL TREATMENTS FOR STROKE
work presented at association of british neurologists meeting
Work by Lancashire Neuroscience researchers on neurology informatics (PhD student Fran Biggin) and the risk of stroke after late-onset epilepsy (Academic Clinical Fellow in Neurology Dr Jasmine Wall) is being presented at the Association of British Neurologists Autumn 2020 virtual conference.
COCHRANE REVIEW HIGHLIGHTS POTENTIAL OF GLP-1 RECEPTOR AGONISTS FOR PARKINSON'S
A recent Cochrane review by Professor Emsley and colleagues at Lancaster University has highlighted the potential of GLP-1 receptor agonists (currently used to treat type 2 diabetes mellitus) as neuroprotective treatments for Parkinson's disease. Dr Richard Wyse (of The Cure Parkinson's Trust) co-authored the report.
PhD STUDENT WORK PRESENTED AT NORTH OF ENGLAND NEUROLOGICAL ASSOCIATION MEETing
Work supervised by Professor Emsley entitled "Routinely collected patient data in neurology research: A systematic mapping review" was presented at the North of England Neurological Association at their annual meeting in November in Harrogate.
LUMBAR PUNCTURE GUIDELINE ADOPTED AS NATIONAL GUIDELINE
Lumbar puncture is commonly used in neurology practice and is used to check the fluid that circulates around the brain and the spinal cord in order to diagnose disorders of the central nervous system. The guideline provides recommendations about lumbar puncture in patients on blood thinning medications. Click here to find out more
Better use of data to improve healthcare
Connected Health Cities North West Coast – part of a £20M 3-year project using information and technology to improve health services for patients across the North of England – this is a partnership between the NWC Academic Health Science Network, AIMES, Lancaster University and the University of Liverpool; its themes include epilepsy, see https://www.connectedhealthcities.org/ and http://www.innovationagencynwc.nhs.uk/connected-health-cities31
Resolving a key question in the early management of acute stroke – HeadPOST trial
UCLan was the UK coordinating centre, and Lancashire Teaching Hospitals NHS Foundation Trust the lead NHS trust in the UK for this international trial of head positioning in acute stroke, which showed no difference in disability outcomes in acute stroke patients who were laid flat vs those sitting up for the first 24 hours. Results were published in June 2018 in the New England Journal of Medicine (NEJM), see http://www.medscape.com/viewarticle/882050