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Research

Neuroscience research in Lancashire is diverse and encompasses the areas outlined below. This includes local studies and projects as well as NIHR portfolio studies, where we are acting as a recruitment centre.

Studies and projects

Brain Tumour North West (BTNW) involves the Universities of Central Lancashire, Wolverhampton, Liverpool and Keele, together with the Lancashire Teaching Hospitals, Clatterbridge Centre for Oncology and Walton Centre NHS Trusts, in a new strategic alliance designed to consolidate and exploit clinical and research-based brain tumour expertise which currently exists within the region.
Brain Tumour North West
Professor Emsley collaborates closely with colleagues on a series of clinical imaging studies.
Clinical neuroimaging studies
Clinical Practice Research Unit (Stroke Care)
Clinical Practice Research Unit (Stroke Care)
ENIGMA-PD-Vasc
ENIGMA-PD-Vasc
We have a number of active and completed projects synthesizing evidence, including national guideline development
Evidence synthesis and guidelines
Lancashire Teaching Hospitals NHS Foundation Trust hosts the regional neurosciences centre, serving a regional population of approximately 1.5 million. It is also the regional provider of interventional stroke treatment, including mechanical thrombectomy. The hospital has a strong track record of recruitment to NIHR portfolio studies in neurosciences, including stroke, with neurosciences as a leading theme, and leading recruiter of patients to studies, for the Trust.
Lancashire Teaching Hospitals NIHR portfolio studies
The North West Coast Genomic Medicine Centre (NWC GMC) has been set up to help gain a better understanding of the genetic causes of cancer and rare diseases. It is part of the government’s 100,000 Genomes Project, which aims to sequence, or analyse, 100,000 genomes from participants with cancer, rare disorders and infectious disease. Lancashire Teaching Hospitals is a NWC GMC partner organisation, and patients with rare disorders (including rare neurological disorders) and cancer (including brain cancer) are participating.
North West Coast Genomic Medicine Centre
One of the first MND Care and Research Centres to be established, with a long track record of delivering high quality clinical research with significant impact.
Preston MND Care and Research Centre
Clinicians lack confidence in ‘high-level’ neurology service data, particularly when these have been generated where there may be a lack of adequate validation.
Using health informatics to improve neurological care

Neurological conditions cause an immense global burden, ranging from the very common headache disorders which affect almost half of the world’s population, to rare but life-limiting disorders such as motor neurone disease. Dementias and neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease will increase over the next 1-2 decades, but effective treatments are largely lacking – so there is an enormous need for neuroscience research.