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Neurological conditions cause an immense global burden, ranging from the very common headache disorders which affect almost half of the world’s population, to rare but life-limiting disorders such as motor neurone disease. Dementias and neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease will increase over the next 1-2 decades, but effective treatments are largely lacking – so there is an enormous need for neuroscience research.